Scientific references:
Vitamin B6, B12, C, D, E, Zn: These vitamins and minerals are well-known for boosting immunity, critical for proper functioning of body organs, including kidneys.
Malus domestica, Citrus limon, Phyllanthus emblica, & Rosa canina: These fruits are excellent source of immunity-boosting vitamin C.
Arctium lappa: Burdock root extract shows kidney protective effect, while promoting healthy renal physiology and function such as through increasing urine volume that helps to eliminate toxic wastes from the body. [Al-Gebaly AS, Pak J Biol Sci, 2017, 20(6): 314-319; European Medicine Agency, in Assessment report on Arctium lappa L., radix, 2010, p. 12]
Aronia melanocarpa: One of the strongest antioxidant fruits in Nature, Aronia berries contain immunity-modulating compounds and protects & maintains healthy body [Int J Mol Sci, 2014, 15(7):11626-36; Molecules, 2013, 18(12):14989-99]
Astragalus membranaceus: Astragalus root is a well-known Chinese traditional herb that boosts immunity and protects healthy body [J Nat Med, 2009, 63(4):421-9; Comparative Study, 1994, 14(11):664-6].
Cinnamonum cassie: Cinnamon barks possess powerful antioxidant and healthy immunity modulating properties. [Am J Chin Med. 2006, 34(3):511-22; Allergy, 1995, 50(12):995-9; Antivir Chem Chemother, 2009, 19(6): 243-55]
Centella asiatica: C. asiatica possesses antioxidant properties that boost cellular health and modulates immune responses.
Curcuma longa: Curcumin, a antioxidant and immune health promoting bioactive constituent of C. longa, has shown renal health protective effects. [J Ren Endocrinol, 2016, 2:e06]
Cuscuta semens: With high content of flavonoids with strong antioxidant properties, cuscuta seeds are used to nourish and strengthen kidney in traditional Chinese use.
Cynara cardunculus (Artichoke): Studies have demonstrated that artichoke has kidney health protective and regenerative effects. [Ben Salem et al., Arch Physiol Biochem, 2022, 128(3):586-592; Alkushi AG, Pharmacogn Mag, 2017, 13(S3): S430–S436].
Diospyros kaki: Persimmon leaf extract suppresses oxidative damage of renal tissues by inducing antioxidant enzymes, while exerting nephroprotective effect against chemical toxicity. [Choi et al., Prev Nutr Food Sci, 2016, 21(4): 378–383], and [Shahat et al., Drug and Chemical Toxicology, 2022, 45(4): 1578-1586]
Drynaria fortunei: Known to nourish the kidney, drynaria flavonoids have shown to possess nephroprotective and kidney function improving effects. [Long et. al., Phytotherapy Research, 2005, 19(5): 422–427]
Elettaria cardamomum: Rich in antioxidant compounds, E. cardamomum showed powerful health-beneficial properties through promotion of healthy immune responses. [Molecules, 2017 Jul 15, 22(7): 1191; Curr Med Mycol, 2016 Jun, 2(2): 8-15]
Equisetum arvense (Horsetail): Traditionally used as a urine volume promoting herb, horsetail extract was found to produce potent and safe diuretic effect in healthy men. [Carneiro et al., Evid Based Complement Alternat Med, 2014: 760683]
Eriobotrya japonica: Loquat leaf lipopolysaccharides can protect kidney function by inhibiting ECM accumulation and protecting against glomerular damage [Lu et al., Am J Transl Res, 2019, 11(6): 3531–3542]
Euterpe oleracea: Loaded with antioxidant compounds, such as anthocyanins, E. oleracea (acai) berry is the richest antioxidant value fruit known. Acai antioxidants are found to fight oxidative stress and cellular & tissue damage [J Agric Food Chem, 2012, 60(4): 1084-93].
Ganoderma lucidum (Reishi): Reishi mushroom is found to promote immune functions and has demonstrated protective effects on kidney health & function [Immunol Invest, 2003, 32(3):201-15; Front Immunol, 2017, 8:87; BMC Cancer, 2015, 15:1011; Geng et al., Chapter 9: Preventive and therapeutic effect of Ganoderma lucidum on kidney injuries and diseases, In Advances in Pharmacology, 2020, 87:257-276]
Linum usitatissimum (Flaxseed): Flaxseed is highly rich in alpha-linolinic acid, the precursor of health-promoting omega 3 fatty acid. It was found to have healthy kidney function promoting properties. [Kidney International, 2003, 64(6):2100-2017]
Panax ginseng: Ginseng, the most popular traditional Chinese & Korean herb with many health benefits, was found to possess renal health protective effects. [Food Chem Toxicol, 2013, 59:153-9]
Pinus pinaster: Bark of P. pinaster is an excellent reservoir of antioxidants. It promote healthy immune responses, and protects and maintains healthy body. [Nutrients, 2019 Jan 22, 11(2): 214; Int J Antimicrob Agents, 2020 Dec, 56(6): 106191]
Piper nigrum: Piper nigrum (black pepper) possess oxidant and healthy immunity promoting properties, while piperine, its major bioactive compound, enhances absorption of beneficial nutrients such as of curcumin, another powerful antioxidant and health-promoting compound found in turmeric. [Arthritis Res Ther, 2009, 11(2): R49]
Polygonum cuspidatum: A powerful antioxidant and healthy immunity promoting herb, P. cuspidatum was shown to reduce harmful immune markers and displayed health protecting bioactions [J Clin Endocrinol Metab, 2010, 95(9):E1-8.20534755; Int J Prev Med, 2013, 4(suppl 1):S1-4.23717757; J Ethnopharmacol, 2013, 148(3):729-745.23707210]
Rosa canina: One of the richest source of immunity boosting vitamin C, rosehip also possesses powerful antioxidant and immune health promoting properties. It has diuretic effects and is good for kidney.
Salvia rosmarinus: Through powerful antioxidant and healthy immunity promoting bioactive compounds, such as rosmarinic and carnosic acid etc., rosemary boosts immune function. [J Agric Food Chem, 2007 Sep 19, 55(19): 7879-85; Future Sci OA, 2018 Apr, 4(4): FSO283]
Sambucus nigra: S. nigra fruits are rich in antioxidant and healthy immunity promoting compounds, and are shown to impart potent health-protective actions [J Int Med Res, Mar-Apr 2004, 32(2): 132-40; Antivir Chem Chemother, 2009, 19(6): 243-55]
Silybum marianum (Milk thistle): Milk thistle was found to have kidney health protective properties. [Rafieian-Kopaie & Nasri, Renal Inj Prev, 2012, 1(1): 3-5]
Syzygium aromaticum: S. aromaticum is loaded with antioxidant and healthy immunity promoting compounds, and is found to possess health-boosting properties [Braz J Microbiol. 2012 Oct-Dec, 43(4): 1255-1260; Asian Pac J Trop Biomed, 2014 Feb, 4(2): 90-96]
Taraxacum officinale (Dandelion): Dandelion leaf extract was found to exert nephroprotective effects via multi-pronged beneficial bioactions. [Badr et al., Dose Response, 2019, 17(3): 1-11]
Uncaria tomentosa: Uncaria, a medicinal herb from the amazon forest, with strong and healthy immune health promoting properties, was shown to have protective effect on renal health. [Rev Esc Enferm USP, 2011; 45(1):189-93]
Urtica dioica (Stinging nettle): Stinging nettle was found to have diuretic effect, and to promote renal salt clearance [Tahri et al., J Ethnopharmacol, 2000, 73(1-2):95-100]
Vaccinium macrocarpon (Cranberry): Cranberry juice drinking showed protective effect on urinary tract health in women [Alvarenga et al., Food Funct, 2019, 10(6):3103-3112]
Vitis vinifera: Grape seed has potent antioxidant and healthy immune health promoting properties as well as high content of vitamin E and omega fatty acid that can offer protective effects on cells and tissues including in kidneys.
Zingiber officinale (ginger): Ginger possesses strong antioxidant and healthy immunity promoting properties and has powerful health-protective properties [Asian Pac J Trop Biomed, 2012 Aug, 2(8): 597–601p
Angeline
My mother’s kidney damage deteriorated to stage 4 with an eGFR reading of 23 in July 2021.
She started taking this product about 3 years ago, and her eGFR gradually increased to 36.