Scientific references:
Vitamin C, D & E: While these vitamins are well-established promoters of immunity, they also promotes and protect bone, joint and muscle tissues through bone mineralization or antioxidant actions.
Calcium: Calcium is the central ingredient in bone tissues.
Magnesium: Involved in numerous cellular processes, Mg2+ also strengthens bones, and helps maintains muscle function & joint cartilage [Nutr Res, 2021, 90:24-35]
Selenium: Well-known for promoting immunity, selenium is also found to promote condrocyte differentiation and regeneration of cartilage tissues in joints [Osteoarthritis Cartilage, 2007,15(10):1171-7]
Zinc: A well-known immunity-boosting mineral, zinc also protect chondrocytes, the key component in cartilage tissues in joints [Nutrients, 2018, 10(4): 471]
Malus domestica, Citrus limon, Phyllanthus emblica, & Rosa canina: These fruits are excellent source of vitamin C, which not only boost immunity, but also collagen synthesis, a key component of bone & joint tissues [Ther Adv Chronic Dis, 2021, 12]
Arctium lappa L (Burdock): Burdock root – a source of powerful antioxidants, such as quercetin, luteolin, & phenolic acids – is found to reduce the levels of oxidative stress and harmful immune markers in individuals with decaying knee conditions. [Int J Rheum Dis, 2014, 19(3):255-261]
Aronia melanocarpa: One of the strongest antioxidant fruits in Nature, Aronia berries has powerful health and immunity boosting properties [Int J Mol Sci, 2014, 15(7):11626-36; Molecules, 2013, 18(12):14989-99]
Astragalus membranaceus: Astragalus is a well-known Chinese medicinal herb known for boosting immunity, which protects and maintains healthy body [J Nat Med, 2009, 63(4):421-9; Comparative Study, 1994, 14(11):664-6].
Bambusa vulgaris (bamboo, leaf): A rich source of silica needed for building healthy skin, joints and cartilage, bamboo leaf extract was found to stimulate collagen synthesis [Exp Ther Med. 2017 Dec; 14(6): 5696–5702]
Boswellia serrata: Compounds found in Boswellia serrata gum has potent immunity-modulating properties, and are found to suppress joint pain [Phytomedicine, 2003, 10(1):3-7; Int J Med Sci, 2011, 8(7):615-622]
Centella asiatica: C. asiatica possesses antioxidant properties that boost cellular health, and also has immune health promoting properties.
Cinnamonum cassie: Cinnamon barks possess powerful antioxidant and immunity-modulating properties with strong health-boosting bioactions [Am J Chin Med. 2006, 34(3):511-22; Allergy, 1995, 50(12):995-9; Antivir Chem Chemother, 2009, 19(6): 243-55]
Cissus quadrangularis: C. quadrangularis extract increases bone density, strength, and calcium content, and was found to have beneficial healing effect on joint pain, swelling, and mobility issues in human subjects [Ayu. 2015 Apr-Jun; 36(2):169-173; Pharmacog Mag, 2016 May, 12(Suppl 2): S213–S217]
Curcuma longa: Curcumin, a powerful anti-inflammatory constituent of C. longa, was found to offer beneficial actions on poor bone health associated knee pain in human subjects. [Trials 20, 214 (2019)]
Cuscuta sinensis (Dodder): Dodder seeds have been found to protect bone tissues from decay and degeneration. [Braz J Med Biol Res, 2019, 52(12):e8754]
Diospyros kaki (Persimmon): Persimmon leaves are excellent sources of antioxidant and healthy immunity promoting properties, such as flavonoids, triterpenoids, tannins, and carotinoids that help protect cells and tissues from damages, the key problem in muscle and joint disorders. [Kor J Pharmacog, 2010, 41(4):255-263; Prev Nutr Food Sci, 2012, 17:14-21]
Dipsacus asper: A traditional Chinese herb used for promoting bone health, recent studies have found that roots of D. asper has bone regenerating nutritional properties [Front. Pharmacol., 29 November 2019; Osteop. Int., 2012, 23:2649–2660]
Drynaria fortunei: Used for improving bone disorders in traditional chinese and korean usage, D. fortunei extracts protected bone mineral density, improved bone structures, and prevented bone decay [Trop J Pharm Res, 2016, 15(7):1447-1452]
Elettaria cardamomum: Rich in antioxidant compounds and immune health promoting bioactions. [Molecules, 2017 Jul 15, 22(7): 1191; Curr Med Mycol, 2016 Jun, 2(2): 8-15]
Euterpe oleracea: Loaded with antioxidant compounds, such as anthocyanins, E. oleracea (acai) berry is the richest antioxidant value fruit known. It fights oxidative stress and promotes health and immunity [J Agric Food Chem, 2012, 60(4): 1084-93].
Eriobotrya japonica (Loquat): Loquat leaf extract stimulates myogenic differentiation and promotes muscle health, and is found to increase grip-strength in healthy individuals [Int J Mol Med, 2015 Sep; 36(3):792-800; Evidence-Based Complementary and Alternative Medicine, 2016, Article ID 4301621]
Gynostemma pentaphyllum: An adaptogenic herb in traditional chinese usage, gynostemma has antioxidant and healthy immunity promoting properties for cellular rejuvenation. It is shown to enhance energy and stamina, and swimming capacity [Journal of Animal and Veterinary Advances, 11:1627-1632]
Panax ginseng: Ginseng was found to reduce both physical and mental stamina in people with long-term fatigue. [PLoS One, 2013 Apr, 8(4):e61271]
Pinus pinaster: Bark of P. pinaster is an excellent reservoir of antioxidants and healthy immunity promoting properties. [Nutrients, 2019 Jan 22, 11(2): 214; Int J Antimicrob Agents, 2020 Dec, 56(6): 106191]
Piper nigrum: Piper nigrum possess antioxidant and immunity-promoting properties, while piperine, its major bioactive compound, also enhances the absorption of nutrients such as curcumin, a powerful health promoting compound in turmeric.
Persea americana (Avocado): A rich source of bone-beneficial vitamin K, avocado (and soybean) saponins were found to improve symptoms associated with poor joint and hip bone tissues. [Clin Rheumatol. 2003; 22: 285-288; Ann Rheum Dis. 2014; 73: 376-384]
Polygonum cuspidatum: P. cuspidatum is a powerful antioxidant and healthy immunity promoting herb with potent health beneficial properties [J Clin Endocrinol Metab, 2010, 95(9):E1-8.20534755; Int J Prev Med, 2013, 4(suppl 1):S1-4.23717757; J Ethnopharmacol, 2013, 148(3):729-745.23707210]
Rehmannia glutinosa: R. glutinosa root possesses healthy immunity promoting and antioxidant properties, and is found to prevent joint problems, such as pain and swelling, while improving joint mobility [In: WHO Monographs on Selected Medicinal Plants, 2007, 3:283-295]. It has also shown to improve bone mineralization, and bone thickness in osteoporosis animal model, while formulations of R. glutinosa with other herbs have shown beneficial effects in people with bone disorders. [J Ethnopharmacol, 2017, 198:351-362]
Salvia rosmarinus: Loaded with powerful antioxidant and healthy immunity promoting micronutriuents (rosmarinic acid and carnosic acid etc.), rosemary possesses potent health-boosting bioactions [J Agric Food Chem, 2007 Sep 19, 55(19): 7879-85; Future Sci OA, 2018 Apr, 4(4): FSO283]
Sambucus nigra: S. nigra fruits are rich in immunity-boosting and antioxidant compounds with potent health-protecting bioactions [J Int Med Res, Mar-Apr 2004, 32(2): 132-40; Antivir Chem Chemother, 2009, 19(6): 243-55]
Syzygium aromaticum: S. aromaticum is loaded with powerful antioxidant and immunity-promoting micronutrients with many health benefits [Braz J Microbiol. 2012 Oct-Dec, 43(4): 1255-1260; Asian Pac J Trop Biomed, 2014 Feb, 4(2): 90-96]
Trigonella foenum-graecum (Fenugreek): Fenugreek seeds have been found to have multifaceted health benefits including prevention of tissue damages associated with joint pain etc. [Food Chem Toxicol, 2012, 50(7):2503-2507; J Reprod Infertil, 2014, 15(1):41–48]
Uncaria tomentosa (Cat’s claw): Uncaria, a powerful health-promoting herb from the amazon forest, has been found to prevent health disorders associated associated poor bone and joint health, such as pain [Phytomedicine, 2001 Jul, 8(4):267-74; Inflamm Res, 2001 Sep; 50(9):442-8]
Vitis vinifera (grape, seed): A rich source of powerful antioxidant compounds, such as phenolic acids, anthocyanins, flavonoids, and oligomeric proanthocyanidin complexes (OPCs) with healthy immunity promoting properties, grape seeds have shown to possess multifaceted health benefits including increasing collagen levels and bone strength, critical for joint health [Int J Mol Sci, 2017, 18(2):376]; Eur J Oral Sci, 2005, 113(1):47-52; Immunol Lett, 2009, 124(2):102-10.]
Zingiber officinale (ginger): It has strong antioxidant and healthy immunity promoting properties. [Asian Pac J Trop Biomed, 2012 Aug, 2(8): 597–601]
John McLean
I have started taking the Bone, Joint and Muscle remedy and this has resulted in stopping arthritic pain in my shoulder that I have had every winter for about eight years.
The winter of 2022 in New Zealand has been particularly cold and damp and yet I have not felt any pain at all. This is obviously a result of the herbal remedy.
— John McLean, author and publisher, New Zealand